KDMSi · in-browser siRNA design

1 · Design job

Target gene name Target transcript (FASTA)

Design mode Modified siRNA (Base3 select → sample chemistry → KDMSi rerank) Naked siRNA (Base3 potency only) User-provided naked siRNAs (sample chemistry → KDMSi rerank)

Advanced parameters

Base3 top N Patterns per core Final top N Sense length Antisense overhang Concentration (nM) Off-target

First run downloads the models (~250 MB) into your browser cache; later runs are instant & offline. Nothing leaves your device.

2 · Pipeline

3 · Results

show raw tokens

Modification notation